FITC标记的赖氨酰氧化酶样1抗体
产品名称： FITC标记的赖氨酰氧化酶样1抗体
英文名称： Anti-LOXL1/FITC
产品编号： HZ-18344R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LOXL1/FITC Conjugated antibody
FITC标记的赖氨酰氧化酶样1抗体
| 英文名称 | Anti-LOXL1/FITC |
| 中文名称 | FITC标记的赖氨酰氧化酶样1抗体 |
| 别 名 | Lysyl oxidase like 1; LOL; LOXL1_HUMAN； LOXL; Lysyl oxidase homolog 1; Lysyl oxidase like 1; Lysyl oxidase like protein 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LOXL1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008] Function: Involved in hearing. Required for normal function of hair cells in the inner ear. Subcellular Location: Secreted, extracellular space. DISEASE: Deafness, autosomal recessive, 77 (DFNB77) [MIM:613079]: A form of non-syndromic deafness characterized by preserved low-frequency hearing, and a trend toward mild to moderate mid-frequency and high-frequency hearing loss during childhood and adolescence. Hearing loss progresses to become moderate to severe at mid and high frequencies during adulthood. Similarity: Contains 14 PLAT domains. Database links: Entrez Gene: 4016 Human Entrez Gene: 16949 Mouse Entrez Gene: 315714 Rat Omim: 153456 Human SwissProt: Q08397 Human SwissProt: P97873 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码赖氨酰氧化酶基因家族的一个成员。该家族的原型成员对于结缔组织的生物发生是必不可少的，编码细胞外铜依赖的胺氧化酶，该酶催化胶原和弹性蛋白形成交联的第一步。在C末端的高度保守的氨基酸序列似乎对胺氧化酶活性足够，表明每个家族成员可能保留这个功能。N端保守性差，可能给每个家族成员在发育调节、衰老、肿瘤抑制、细胞生长控制和趋化性方面赋予额外的作用。[ RefSeq，JUL 2008 ]