免疫病理miRNAPCR芯片用于研究在正常和病理反应的免疫系统中差异表达的84个 miRNA的表达。这个芯片为免疫学研究人员提供了一个快速方便的方法来分析与淋巴细胞和其他免疫细胞的功能最相的miRNA。miRNA的精心挑选基于已经发表的文献，这些miRNA显示与炎症,白血病,淋巴瘤,自身免疫性疾病,或其他免疫反应相关。这个芯片还包括以转录编码细胞因子的基因为功能性靶点的miRNA，以及其它免疫调节蛋白,免疫反应信号通路组件的miRNA。这芯片分析结果可作为研究正常和疾病有关的免疫反应的分子标记。结果也能更深入了解的miRNA分子调节免疫基因表达的调节机制每张芯片含一个对照组使得分析数据时可以用相对定量ΔΔCT方法评估逆转录效率,基因组DNA污染,和PCR效率。利用这张芯片，通过实时定量PCR，可以简易且可靠地分析免疫病理学相关的niRNA的表达。

miScript miRNA PCR芯片仅用于分子生物学应用。本产品不用于疾病的诊断、预防和治疗。

提供96孔板——384 -(4 x 96)板,和100孔板。

Leukemia & Lymphoma: 
Hodgkin's Lymphoma: miR-125b-5p, miR-126-3p, miR-128, miR-130a-3p, miR-132-3p, miR-134, miR-135a-5p, miR-135b-5p, miR-138-5p, miR-142-3p, miR-142-5p, miR-145-5p, miR-147a, miR-15b-5p, miR-181a-5p, miR-183-5p, miR-185-5p, miR-200a-3p, miR-205-5p, miR-20b-5p, miR-21-5p, miR-23b-3p, miR-26a-5p, miR-26b-5p, miR-27a-3p, miR-29b-3p, miR-302a-3p, miR-30c-5p, miR-31-5p, miR-325, miR-335-5p, miR-34a-5p, miR-9-5p.
Other: miR-15a-5p.
Primary Effusion Lymphoma: miR-103a-3p, miR-106a-5p, miR-142-3p, miR-148a-3p, miR-152, miR-16-5p, miR-182-5p, miR-186-5p, miR-191-5p, miR-194-5p, miR-19a-3p, miR-210, miR-23b-3p, miR-26a-5p, miR-29b-3p, miR-30e-5p, miR-34a-5p.
T-cell Leukemia: miR-106a-5p, miR-132-3p, miR-18b-5p, miR-19b-3p, miR-20b-5p, miR-363-3p.

Autoimmune Disorders: 
Idiopathic Thrombocytopenic Purpura: miR-196a-5p, miR-214-3p, miR-298, miR-299-3p, miR-379-5p, miR-383, miR-409-3p.
Systemic Lupus Erythematosus: miR-142-3p, miR-184, miR-196a-5p, miR-21-5p, miR-298, miR-299-3p, miR-383, miR-409-3p.

Inflammatory Responses: 
IL-1 Induced Inflammatory Response: let-7g-5p, miR-146a-5p, miR-195-5p, miR-26b-5p.
Inflammation Mediators: miR-155-5p, miR-203a.
Macrophage Inflammatory Response: miR-132-3p, miR-155-5p.
Vascular Inflammation: miR-126-3p, miR-155-5p, miR-21-5p.
Others: miR-125a-5p.

Innate Immune Response: miR-105-5p, miR-146a-5p, miR-19a-3p, miR-19b-3p.

Induced in Monocytes By LPS: let-7e-5p, miR-132-3p, miR-146a-5p, miR-155-5p, miR-187-3p, miR-9-5p, miR-99b-5p.

Immune Cells: 
B Cell Differentiation: miR-150-5p.
Invariant Natural Killer Cell Development: miR-155-5p, miR-150-5p.
Lymphocytes: let-7e-5p, miR-125a-5p, miR-142-5p, miR-143-3p, miR-145-5p, miR-146a-5p, miR-148a-3p, miR-195-5p, miR-206, miR-223-3p, miR-451a, miR-493-3p, miR-574-3p.
Monocytopoiesis: miR-106a-5p, miR-20a-5p.
Natural Regulatory T Cells: miR-103a-3p, miR-142-5p, miR-149-5p, miR-150-5p, miR-15b-5p, miR-16-5p, miR-191-5p, miR-19a-3p, miR-21-5p, miR-214-3p, miR-223-3p, miR-26a-5p, miR-27b-3p, miR-29c-3p, miR-30b-5p, miR-30c-5p, miR-30e-5p.
Th2 Cells: miR-126-3p.

Regulates Relevant Genes: 
Cytokines: miR-98-5p.
Interferons & Receptors: miR-146a-5p, miR-223-3p.
Interleukins: miR-106a-5p, miR-146a-5p, miR-155-5p, miR-15a-5p, miR-181a-5p, miR-223-3p, miR-223-3p.
STAT3: miR-18a-5p, miR-19a-3p, miR-19b-3p, miR-20a-5p.
TNF Alpha: miR-125b-5p, miR-155-5p.

Signal Transduction: 
IL6 / STAT3 Signaling: let-7a-5p, let-7c, let-7d-5p, miR-21-5p.
NFKB Signaling: miR-146a-5p, miR-155-5p.