FITC标记的核孔复合蛋白Nup155抗体
产品名称： FITC标记的核孔复合蛋白Nup155抗体
英文名称： Anti-NUP155/FITC
产品编号： HZ-19543R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NUP155/FITC Conjugated antibody
FITC标记的核孔复合蛋白Nup155抗体
| 英文名称 | Anti-NUP155/FITC |
| 中文名称 | FITC标记的核孔复合蛋白Nup155抗体 |
| 别 名 | 155 kDa nucleoporin; D930027M19Rik; KIAA0791; mKIAA0791; N155; NU155_HUMAN; Nuclear pore complex protein Nup155; nucleoporin 155kD; Nucleoporin Nup155; Nup155. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 染色质和核信号 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Zebrafish, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 155kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NUP155 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013] Function: Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport. Subcellular Location: Nucleus > nuclear pore complex. Nucleus membrane. Nucleus membrane. In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing back into a punctate nuclear surface localization at the end of mitosis. Tissue Specificity: Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Post-translational modifications: Phosphorylated. Phosphorylation and dephosphorylation may be important for the function of NUP155 and may play a role in the reversible disassembly of the nuclear pore complex during mitosis. Similarity: Belongs to the non-repetitive/WGA-negative nucleoporin family. Database links: Entrez Gene: 9631 Human Entrez Gene: 427443 Chicken Entrez Gene: 461913 Chimpanzee Entrez Gene: 506738 Cow Entrez Gene: 479360 Dog Entrez Gene: 101133763 Gorilla Entrez Gene: 100053405 Horse Entrez Gene: 170762 Mouse Entrez Gene: 100437988 Orangutan Entrez Gene: 100517061 Pig Entrez Gene: 100347238 Rabbit Entrez Gene: 117021 Rat Entrez Gene: 706019 Rhesus monkey Entrez Gene: 380494 Xenopus laevis Entrez Gene: 100379911 Xenopus tropicalis Omim: 606694 Human SwissProt: O75694 Human SwissProt: Q99P88 Mouse SwissProt: P37199 Rat Unigene: 547696 Human Unigene: 295168 Mouse Unigene: 11328 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
核孔蛋白是在核孔复合物（NPC）的组装和功能中发挥重要作用的蛋白质，NPC调节大分子穿过核膜（NE）的运动。该基因编码的蛋白在NE囊泡的融合和双膜NE的形成中起作用。蛋白质也可能参与心脏生理学，并可能与心房颤动的发病机制有关。选择性剪接导致该基因的多个转录变体。与此基因相关的假基因位于6号染色体上。[ RefSeq，2013年5月提供]