MAL polyclonal antibody
产品名称： MAL polyclonal antibody
英文名称： MAL polyclonal antibody
产品编号： PAB7300
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of MAL.
- Immunogen:
- A synthetic peptide corresponding to human MAL.
- Sequence:
- C-QDGFTYRHYHEN
- Host:
- Goat
- Theoretical MW (kDa):
- 16.7, 12.1, 10.6
- Specificity:
- This antibody is expected to recognize isoform a (NP_002362.1) and isoform c (NP_071884.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:4000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis.
Khor CC, Chapman SJ, Vannberg FO, Dunne A, Murphy C, Ling EY, Frodsham AJ, Walley AJ, Kyrieleis O, Khan A, Aucan C, Segal S, Moore CE, Knox K, Campbell SJ, Lienhardt C, Scott A, Aaby P, Sow OY, Grignani RT, Sillah J, Sirugo G, Peshu N, Williams TN, Maitland K, Davies RJ, Kwiatkowski DP, Day NP, Yala D, Crook DW, Marsh K, Berkley JA, O'Neill LA, Hill AV.Nat Genet. 2007 Apr;39(4):523-8. Epub 2007 Feb 25.
- Application Image
- ELISA
- Entrez GeneID:
- 4118
- Protein Accession#:
- NP_002362.1;NP_071884.1
- Gene Name:
- MAL
- Gene Alias:
- -
- Gene Description:
- mal, T-cell differentiation protein
- Omim ID:
- 188860
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq
- Other Designations:
- T-cell differentiation protein MAL,T-lymphocyte maturation-associated protein,myelin and lymphocyte protein