HK1 monoclonal antibody, clone 7A7
产品名称： HK1 monoclonal antibody, clone 7A7
英文名称： HK1 monoclonal antibody, clone 7A7
产品编号： MAB10682
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant HK1.
- Immunogen:
- Recombinant protein corresponding to human HK1.
- Host:
- Mouse
- Theoretical MW (kDa):
- 102
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis using HK1 monoclonal antibody, clone 7A7 (Cat # MAB10682) against Jurkat (1) , HeLa (2) , HepG2 (3) , MCF-7 (4) and PC-12 (5) cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human salivary gland tissues (upper) and kidney tissues (bottom) using HK1 monoclonal antibody, clone 7A7 (Cat # MAB10682) with DAB staining.
- Entrez GeneID:
- 3098
- Gene Name:
- HK1
- Gene Alias:
- HK1-ta,HK1-tb,HK1-tc,HKI,HXK1
- Gene Description:
- hexokinase 1
- Omim ID:
- 142600
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019725,brain form hexokinase,glycolytic enzyme
- Gene Pathway
- Amino sugar and nucleotide sugar metabolism
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Fructose and mannose metabolism
- Galactose metabolism
- Glycolysis / Gluconeogenesis
- Insulin signaling pathway
- Metabolic pathways
- Starch and sucrose metabolism
- Streptomycin biosynthesis
- Type II diabetes mellitus