FITC标记的硫酸软骨素酶2抗体-抗体-抗体-生物在线
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FITC标记的硫酸软骨素酶2抗体

FITC标记的硫酸软骨素酶2抗体

商家询价

产品名称: FITC标记的硫酸软骨素酶2抗体

英文名称: Anti-CHSS2/FITC

产品编号: HZ-13928R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-CHSS2/FITC Conjugated antibody

FITC标记的硫酸软骨素酶2抗体

 

英文名称 Anti-CHSS2/FITC
中文名称 FITC标记的硫酸软骨素酶2抗体
别    名 Chondroitin glucuronyltransferase II; Chondroitin polymerizing factor; Chondroitin sulfate synthase 2; CHPF; CHSY2; CSS2; CHSS2_HUMAN; Glucuronosyl N acetylgalactosaminyl proteoglycan 4 beta N acetylgalactosaminyltransferase II; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase II.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 85kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CHSS2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
CHSS2 belongs to the chondroitin N-acetylgalactosaminyltransferase family. It has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity and transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. CHSS2 is ubiquitous; highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.

Function:
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress.

Subunit:
Binds CHSY1. Isoform 1, isoform 2 and isoform 3 interact with PARK2.

Subcellular Location:
Golgi apparatus, golgi stack membrane; Single pass type II membrane protein.

Tissue Specificity:
Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, spleen and placenta. Isoform 3 is also ubiquitous. Isoform 2 is expressed in brain, spleen, ovary, testis, lung and peripheral mononuclear cells.

Similarity:
Belongs to the chondroitin N-acetylgalactosaminyltransferase family.

Database links:

Entrez Gene: 79586 Human

Entrez Gene: 74241 Mouse

Entrez Gene: 316533 Rat

Omim: 610405 Human

SwissProt: Q8IZ52 Human

SwissProt: Q6IQX7 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

这一基因编码一个主治样结构域的蛋白质。该蛋白可作为转录共激活剂发挥作用。这种基因的突变是X连锁尿道下裂2型的原因。交替剪接导致多个转录变体。[由RefSeq,APR 2010提供]