FITC标记的硫酸软骨素酶2抗体
产品名称: FITC标记的硫酸软骨素酶2抗体
英文名称: Anti-CHSS2/FITC
产品编号: HZ-13928R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-CHSS2/FITC Conjugated antibody
FITC标记的硫酸软骨素酶2抗体
英文名称 | Anti-CHSS2/FITC |
中文名称 | FITC标记的硫酸软骨素酶2抗体 |
别 名 | Chondroitin glucuronyltransferase II; Chondroitin polymerizing factor; Chondroitin sulfate synthase 2; CHPF; CHSY2; CSS2; CHSS2_HUMAN; Glucuronosyl N acetylgalactosaminyl proteoglycan 4 beta N acetylgalactosaminyltransferase II; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase II. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 85kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CHSS2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: CHSS2 belongs to the chondroitin N-acetylgalactosaminyltransferase family. It has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity and transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. CHSS2 is ubiquitous; highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta. Function: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress. Subunit: Binds CHSY1. Isoform 1, isoform 2 and isoform 3 interact with PARK2. Subcellular Location: Golgi apparatus, golgi stack membrane; Single pass type II membrane protein. Tissue Specificity: Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, spleen and placenta. Isoform 3 is also ubiquitous. Isoform 2 is expressed in brain, spleen, ovary, testis, lung and peripheral mononuclear cells. Similarity: Belongs to the chondroitin N-acetylgalactosaminyltransferase family. Database links: Entrez Gene: 79586 Human Entrez Gene: 74241 Mouse Entrez Gene: 316533 Rat Omim: 610405 Human SwissProt: Q8IZ52 Human SwissProt: Q6IQX7 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
这一基因编码一个主治样结构域的蛋白质。该蛋白可作为转录共激活剂发挥作用。这种基因的突变是X连锁尿道下裂2型的原因。交替剪接导致多个转录变体。[由RefSeq,APR 2010提供]